CRP from 12.4 to 0.8 — 12 month update

A narrower follow-up, since the general answer is now clear:

How would you tell the difference between that and the alternative explanation?

PharmHunterJen said:

Update — I was wrong in the opening post, specifically about the direction.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

PharmHunterJen said:

Update — I was wrong in the opening post, specifically about the direction.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

PharmHunterJen said:

Update — I was wrong in the opening post, specifically about the direction.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Adding it to my notes with a link back to this thread.

Adding the clinical framing, because it changes how the question reads. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.