Yoga and GLP-1 — my results so far

newstart_MO said:

DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.

Same pattern here, and in the same order.

newstart_MO said:

DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.

Regarding lean mass: I accidentally injected my dose intramuscularly instead of subcutaneously last week (went in at wrong angle, too deep). Called my pharmacist — they said it's not dangerous but may absorb faster, potentially causing more GI effects.

Sure enough, had worse nausea that day. Lesson learned: pinch the skin properly and use the right needle length for your body composition.

newstart_MO said:

DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.

newstart_MO said:

...the muscle loss concern with lean mass...

This is a legitimate and well-studied concern. Let me put some numbers on it:

In STEP 1, approximately 39% of weight lost was lean mass. However, the Lundgren 2024 study showed that structured resistance training reduced this to ~25% lean mass loss.

Context matters: at BMI 35+, you're carrying excess lean mass to support the extra weight. Losing some lean mass is expected and not inherently harmful if you maintain adequate muscle function through exercise.

The solution isn't avoiding the medication — it's combining it with proper exercise and protein intake.

Following on from newstart_MO — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

lisa_labSD said:

newstart_MO said: ...the muscle loss concern with lean mass...

Sharing my comprehensive lab data relevant to lean mass:

Protocol: Tirzepatide 10mg/wk, resistance training 5x/week, protein 1.5g/kg/day.

The improvements in lean mass are clearly reflected in these numbers. The inflammatory marker reduction (hsCRP) is particularly striking.