🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSemaglutide (Ozempic / Wegovy)Month 2 and I have lost NOTHING - normal?? — looking for input Page 2

Month 2 and I have lost NOTHING - normal?? — looking for input

roxy_nash Wed, Feb 7, 2024 at 7:52 PM 37 replies 2,431 viewsPage 2 of 8
InsuranceTom
Senior Member
1,345
7,890
Mar 2024
Connecticut
Feb 8, 2024 at 7:39 PM#6
amsterdam_pete said:
The dose-response is real but shallow at the top.

I will push back on the "any working dose is fine" framing. The maintenance evidence sits overwhelmingly at the top studied dose, and the extension data shows regain tracking dose reduction rather than tracking stopping. Holding low is reasonable; pretending it is evidentially equivalent is not.

Last edited: Feb 9, 2024 at 12:39 AM
46 16lisa_labSD, adam_van, Dr.SurgeonPGH and 43 others
Reply Quote Save Share Report
FDA_TrackerJim
Senior Member
1,567
7,890
Feb 2024
Rockville, MD
Feb 9, 2024 at 5:07 AM#7

Adding the numbers, since they settle part of this. Worth knowing that the injection site changes very little. Abdomen, thigh and upper arm are bioequivalent for semaglutide, so a site change is not a plausible explanation for a bad week.

45 15Admin, Dr.Martinez, mike_mod and 42 others
Reply Quote Save Share Report
MASHdoc_SA
Member
456
2,345
Aug 2024
San Antonio, TX
Feb 9, 2024 at 2:35 PM#8
InsuranceTom said:
I will push back on the "any working dose is fine" framing.

There is a second half to this that has not been said yet. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Last edited: Feb 9, 2024 at 5:35 PM
44 14JennaRN, LabKate, kate.chem and 41 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
Dr.EndoEP
Member
267
1,234
Oct 2024
El Paso, TX
Feb 10, 2024 at 12:03 AM#9

One thing that is still open after Dr.EM_Chicago’s answer:

How long did you give it before you decided it was working?

Last edited: Feb 10, 2024 at 2:03 AM
43 13Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 40 others
Reply Quote Save Share Report
roxy_nash
Member
178
890
Dec 2024
Nashville, TN
Feb 11, 2024 at 9:33 PM#10

Closing the loop on my own question.

Six weeks on from posting: I stopped reading the weekly number and started reading a four-week average, and the "stall" I opened this thread about was a 1.8kg loss I could not see.

Last edited: Feb 12, 2024 at 3:33 AM
43 16kim_atl_prep, sarah_TO, wendy_avl and 40 others
Reply Quote Save Share Report

Similar Threads

STEP 1-5 trials comprehensive summary — efficacy endpoints compiled12 replies
Oral semaglutide 50mg Phase 3 — OASIS program results16 replies
Semaglutide pharmacokinetics — half-life, Tmax, steady state modeling10 replies
Compounded semaglutide stability data — temperature and light sensitivity16 replies
0.25mg → 2.4mg titration: optimal schedule based on clinical data6 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register