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ForumsSide Effects & ManagementWhen to stop GLP-1 — need advice Page 3

When to stop GLP-1 — need advice

pam_stl Mon, Oct 20, 2025 at 2:04 AM 39 replies 1,952 viewsPage 3 of 8
PharmD_Rodriguez
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Oct 22, 2025 at 9:12 PM#11
DeniseRN_TPA said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

44 17paul_denver, TinaHashiRN, robert_kc and 41 others
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TomFromTexas
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May 2024
Austin, TX
Oct 23, 2025 at 11:37 AM#12
DanielChem_CHI said:
Agreed on adaptation, with a caveat: adaptation applies to gastric emptying and not to everything.

Bookmarking. The distinction being drawn above is the one nobody else makes. Taking it to my next appointment.

45 18Dr.NateNeph, PharmD_Rodriguez, julia.endo and 42 others
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mark_tokyo
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Oct 24, 2025 at 2:02 AM#13
DeniseRN_TPA said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

46 19LibrarianMeg, bri_stats, pete_manc_UK and 43 others
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josh_phd_bmore
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Oct 24, 2025 at 4:28 PM#14

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

47 20KarenAZ_mom, zoe_NC, Dr.ObesityLA and 44 others
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mike_mod
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Oct 25, 2025 at 6:54 AM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

48 21PurityPaulOR, MaxMetOK, MounjBrad and 45 others
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