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ForumsSemaglutide (Ozempic / Wegovy)Oral semaglutide 25mg vs 50mg — looking for input Page 5

Oral semaglutide 25mg vs 50mg — looking for input

pam_stl Thu, May 30, 2024 at 9:03 AM 55 replies 2,751 viewsPage 5 of 11
Dr.PeteFamMed
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Jun 4, 2024 at 4:28 AM#21

Adding the numbers, since they settle part of this. Worth knowing that the injection site changes very little. Abdomen, thigh and upper arm are bioequivalent for semaglutide, so a site change is not a plausible explanation for a bad week.

Last edited: Jun 4, 2024 at 5:28 AM
12 10hyun_seoul, jim_asheville, matt_MKE and 9 others
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robert_kc
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Jun 5, 2024 at 12:29 AM#22

One thing that is still open after Dr.NateNeph’s answer:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

13 11SleepFixSam, PurityPaulOR, MaxMetOK and 10 others
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JennaRN
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Jun 5, 2024 at 8:30 PM#23
Dr.PeteFamMed said:
Worth knowing that the injection site changes very little.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

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Dr.NutriCornell
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Jun 6, 2024 at 4:30 PM#24
Dr.PeteFamMed said:
Worth knowing that the injection site changes very little.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

Correct me if the detail matters more than I have assumed.

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NeuroNate
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Jun 7, 2024 at 12:30 PM#25
Dr.PeteFamMed said:
Worth knowing that the injection site changes very little.

That reframing is the part I needed.

Last edited: Jun 7, 2024 at 6:30 PM
16 14Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 13 others
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