MASH biomarker panel — looking for input

Dr.PainCLE said:

The single most useful discipline is bringing the whole panel to a clinician rather than one flagged value.

Saving this. It is the first explanation that did not require me to already understand it. Printing the relevant bit and taking it with me.

Clinical perspective, offered as context rather than as advice.

Shot day Wednesday report relevant to baseline bloodwork:

Week 49. Currently on 10mg. Down 65 lbs from starting weight of 277 lbs.

This week's observations: Mild fatigue day 1-2 post-injection, then fine.

Labs due next week — looking forward to seeing the metabolic panel. I'll post results in the Lab Results section when they come in.

Dr.NephBHM_UK said:

The liver data is among the strongest non-weight findings in the class.

PSA: get baseline labs BEFORE starting baseline bloodwork therapy. You need a "before" picture to measure progress. My recommended pre-treatment panel:

1. CMP + A1C + fasting insulin
2. Complete lipid panel with particle count if possible
3. hsCRP, ferritin, B12, vitamin D
4. Thyroid panel (TSH + free T4)
5. CBC with differential
6. Liver panel (ALT, AST, GGT)
7. DEXA scan or body composition

Total cost at Quest without insurance: ~$200. Worth every penny for the data.

tammy_FL said:

Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c…

Blood work came back perfect. baseline bloodwork + this community = winning. 🏆

Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.