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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide and alcohol intolerance — anyone have experience? Page 4

Semaglutide and alcohol intolerance — anyone have experience?

Dr.SurgeonPGH Wed, Jun 26, 2024 at 6:29 AM 16 replies 2,151 viewsPage 4 of 4
FranDenver
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Jun 27, 2024 at 10:51 PM#16
Dr.EndoIndy said:
Dr.SurgeonPGH said: ...but the FDA says semaglutide...

Agreed, and if the change has opened a harder question about someone's drinking, that belongs with a service rather than a thread.

Last edited: Jun 28, 2024 at 4:51 AM
7 5Dr.RenalNash, LipidDoc_ATL, BariatricNurseD and 4 others
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GenomicsKate
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Jun 28, 2024 at 4:33 AM#17

Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Jun 28, 2024 at 9:33 AM
8 6KristenIndy, MarkLI_maint, Dr.PeteFamMed and 5 others
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PharmD_Rodriguez
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Jun 28, 2024 at 10:15 AM#18
GenomicsKate said:
The mechanism and the magnitude are separate questions.

Adding a me-too, because a thread of one person's experience is not much use. Nothing to add that would improve it.

9 7robert_kc, dan_philly, MeganSA_TX and 6 others
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Dr.RenalNash
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Jun 28, 2024 at 3:57 PM#19
GenomicsKate said:
The mechanism and the magnitude are separate questions.

Coming at GenomicsKate’s question from a different direction. Reduced interest in alcohol is one of the most consistently reported off-target effects, and the mechanism is plausibly the same reward-salience pathway that quiets food noise. The practical part people get wrong is that tolerance changes: less food in the stomach, faster gastric emptying of liquid relative to solids, and a smaller body mean the same two drinks land considerably harder than they used to.

Last edited: Jun 28, 2024 at 8:57 PM
10 8anders_CPH, Dr.NutriCornell, pam_stl and 7 others
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mike_mod
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Jun 28, 2024 at 9:39 PM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. No action needed from anybody.

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