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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseHas anyone dealt with fibrosis regression on glp-1? Page 7

Has anyone dealt with fibrosis regression on glp-1?

JenMemphis Sat, Apr 26, 2025 at 7:21 PM 46 replies 1,810 viewsPage 7 of 10
SurmountFan_IN
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May 10, 2025 at 12:23 AM#31
SarahChen_PharmD said:
Start from the measurement rather than the conclusion.

Adding the part of the answer the thread has not reached. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

20 18DebRD_ATL, KristenIndy, MarkLI_maint and 17 others
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Dr.GutHealth
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May 10, 2025 at 7:51 PM#32

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

That is the short version; the long version is somebody else's post.

21 19tyler_CSCS, VanRx_Mike, steve_okc and 18 others
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wei_SG
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May 11, 2025 at 3:20 PM#33

One thing that is still open after SarahChen_PharmD’s answer:

What did you change at the same time, and can you separate the two now?

22 20Dr.MetabolicMD, RetaRick_CA, JenPlateau and 19 others
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NurseLeah_Nash
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May 12, 2025 at 10:49 AM#34
Dr.GutHealth said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

Last edited: May 12, 2025 at 11:49 AM
23 21Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 20 others
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TrialNerd_Beth
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May 13, 2025 at 6:18 AM#35
Dr.GutHealth said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

Last edited: May 13, 2025 at 10:18 AM
24 22SleepFixSam, PurityPaulOR, MaxMetOK and 21 others
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