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ForumsSide Effects & ManagementAcid reflux/GERD worsening on GLP-1 — my results so far Page 2

Acid reflux/GERD worsening on GLP-1 — my results so far

JessicaM_2024 Sat, Jan 10, 2026 at 7:30 AM 40 replies 1,616 viewsPage 2 of 8
BethLabQueen
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Jan 10, 2026 at 9:20 AM#6
NurseKim_ATL said:
The practical protocol is dull and it works: smaller meals, stop eating at the first sign of fullness rather than at the end of the plate, drop the…

I dislike how confidently this board tells people to push through. Incidence figures around 20 to 25% at the higher doses are class-typical, but the trials also had a discontinuation column, and "manageable with protocols" is not the same as manageable for everyone.

38 8maya_sedona, stefan_berlin, Dr.EM_Chicago and 35 others
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LabKate
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Jan 10, 2026 at 10:03 AM#7

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Jan 10, 2026 at 1:03 PM
37 7laura_annarbor, JenMemphis, pat_auckland and 34 others
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VanRx_Mike
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Jan 10, 2026 at 10:46 AM#8
BethLabQueen said:
I dislike how confidently this board tells people to push through.

Coming at BethLabQueen’s question from a different direction. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

I would rather be corrected than agreed with, if it comes to it.

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FitDadDave
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Jan 10, 2026 at 11:29 AM#9

One thing that is still open after DataDave’s answer:

Whether holding at a lower dose for longer actually reduces total side-effect burden or just spreads it out?

35 5wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 32 others
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JessicaM_2024
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Jan 10, 2026 at 2:56 PM#10

OP back with an update, since a thread like this is useless without one.

Holding the step for six weeks instead of four did it. Same dose, same food, and the nausea that had felt like a wall turned out to be a timing problem.

Last edited: Jan 10, 2026 at 3:56 PM
21 19kevin_tulsa, Dr.PainCLE, mike_mealprep and 18 others
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