Adding the clinical framing, because it changes how the question reads. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.
josh_phd_bmore said:If you are going to change something, change one thing and give it long enough to express itself.
That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.
josh_phd_bmore said:If you are going to change something, change one thing and give it long enough to express itself.
Thank you for spelling out the reasoning rather than just the conclusion. I will report back once I have actually tried it.
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View ResultsFrom the other side of the consultation, briefly. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. No action needed from anybody.