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ForumsSide Effects & ManagementConstipation on GLP-1: pathophysiology and fiber protocol — looking for input Page 3

Constipation on GLP-1: pathophysiology and fiber protocol — looking for input

mia_MS2 Fri, Mar 20, 2026 at 4:08 AM 13 replies 847 viewsPage 3 of 3
TirzTom
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Mar 21, 2026 at 2:00 AM#11
VanRx_Mike said:
Heartburn management on constipation: Gaviscon before bed has been my savior.

Sulfur burps on constipation — the most underrated side effect nobody warned me about. 🤢 The smell is absolutely vile and comes on without warning.

What finally helped: Gas-X (simethicone) daily. Also, eating smaller portions and chewing thoroughly reduces the gas production.

If sulfur burps persist beyond 2-3 weeks, talk to your provider — it could indicate gastroparesis that needs medical attention.

17 15josh_phd_bmore, roxy_nash, tony_orlando and 14 others
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greg_boulder
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Mar 21, 2026 at 1:31 PM#12
wei_SG said:
Gastric emptying studies and constipation: semaglutide delays gastric emptying by ~40% at steady state, as measured by acetaminophen absorption…

Genuinely useful, thank you. I had the facts and not the framework.

Last edited: Mar 21, 2026 at 3:31 PM
18 16fiona_VT, denise_HTX, raj_cambridge and 15 others
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TinaHashiRN
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Mar 22, 2026 at 1:02 AM#13
VanRx_Mike said:
Heartburn management on constipation: Gaviscon before bed has been my savior.

Acid reflux and constipation: I developed GERD symptoms around week 7 that I'd never had before. The delayed gastric emptying means food and acid sit in your stomach longer.

Management that works for me: elevate head of bed 6 inches, don't eat within 3 hours of lying down, avoid trigger foods (tomato, citrus, spicy, chocolate), and famotidine 20mg at bedtime. Much better now.

19 17Dr.Martinez, mike_mod, SarahChen_PharmD and 16 others
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FDA_TrackerJim
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Mar 22, 2026 at 12:32 PM#14

Adding the numbers, since they settle part of this. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Mar 22, 2026 at 3:32 PM
20 18Dr.LeslieOBGYN, MikeNYC_runner and 17 others
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Admin
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Mar 23, 2026 at 12:02 AM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

21 19PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 18 others
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