Ipamorelin vs Tesamorelin — anyone have experience?

pat_auckland said:

I want to add the drug interaction perspective on the pharmacology.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

MASHdoc_SA said:

The mechanism is more central than most summaries suggest.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Adding it to my notes with a link back to this thread.

pat_auckland said:

I want to add the drug interaction perspective on the pharmacology.

This is where I part company with the consensus forming above. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.