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ForumsMASH / Liver DiseaseFibrosis regression on GLP-1 — looking for input Page 3

Fibrosis regression on GLP-1 — looking for input

oliver_london Mon, Nov 10, 2025 at 9:38 PM 23 replies 1,403 viewsPage 3 of 5
AmyNC_wife
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Nov 15, 2025 at 12:00 AM#11
MASHdoc_SA said:
ATTAIN trial (survodutide) context for liver and MASH: survodutide, a GLP-1/glucagon dual agonist, showed -18.7% body weight at 46 weeks in the Phase…

Genuinely useful, thank you. I had the facts and not the framework.

19 17JessicaM_2024, TomFromTexas, mike.trainer_LA and 16 others
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Dr.KarenChen
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Nov 16, 2025 at 5:57 AM#12

Clinical perspective, offered as context rather than as advice. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

20 18JessicaM_2024, TomFromTexas, mike.trainer_LA and 17 others
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COA_Karl
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Nov 17, 2025 at 11:54 AM#13
Dr.GastroMayo said:
Liver imaging follow-up for liver and MASH: FibroScan at baseline showed CAP score 326 dB/m (moderate steatosis) and stiffness 10.8 kPa (possible…

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

21 19hyun_seoul, jim_asheville, matt_MKE and 18 others
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DanielChem_CHI
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Nov 18, 2025 at 5:50 PM#14

The figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

22 20ben_calgary, patPC_UT, Dr.DermMIA and 19 others
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mike_mod
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Nov 19, 2025 at 11:46 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.

Last edited: Nov 20, 2025 at 1:46 AM
23 21PurityPaulOR, MaxMetOK, MounjBrad and 20 others
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