From the other side of the consultation, briefly. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
Ask again with the specifics and you will get a better answer than this one.
A narrower follow-up, since the general answer is now clear:
Was that from a primary source or from a summary of one?
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Browse GL BiochemPharmacoVig_BOS said:If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Albumin binding above 99% is the whole reason weekly dosing works, and it is also why the trough matters more than the peak. People who dose late are not losing a peak, they are letting the trough fall, and the appetite effect tracks the trough.
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