DeniseRN_TPA said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.
That is the short version; the long version is somebody else's post.
josh_phd_bmore said:The mechanism is more central than most summaries suggest.
This answered a question I did not know how to ask. Adding it to my notes with a link back to this thread.
DeniseRN_TPA said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.
That is the short version; the long version is somebody else's post.
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Browse GL BiochemThe figures, for anyone assembling their own picture. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.