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ForumsOther Peptides & Research CompoundsMy rabbit hole into peptides started with sema and now look at me — what worked for you? Page 3

My rabbit hole into peptides started with sema and now look at me — what worked for you?

Dr.PulmRoch Sat, Apr 5, 2025 at 7:59 PM 15 replies 1,638 viewsPage 3 of 3
ZaraB_AL
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1,678
Jan 2025
Alabama
Apr 8, 2025 at 12:39 AM#11
andrew_nyc said:
Amycretin (AMY/GLP-1 dual agonist) emerging data relevant to the pharmacology: Phase 1 showed -13.1% body weight at only 12 weeks, the fastest…

This is exactly what I could not find anywhere else. I will report back once I have actually tried it.

33 6JessicaH_TX, KevinCompounds, TirzTom and 30 others
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Dr.LeslieOBGYN
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2,567
May 2024
Dallas, TX
Apr 8, 2025 at 4:53 AM#12

Adding the clinical framing, because it changes how the question reads. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

34 7FranDenver, Dr.BariatricHTX, LindaRN_retired and 31 others
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LabKate
Senior Member
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11,234
Jan 2024
Oregon
Apr 8, 2025 at 9:07 AM#13
Dr.SurgeonPGH said:
Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…

This is where I part company with the consensus forming above. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

35 8Dr.SleepRoch, laura_annarbor, JenMemphis and 32 others
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stefan_berlin
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Oct 2024
Berlin, DE
Apr 8, 2025 at 1:21 PM#14

The figures, for anyone assembling their own picture. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

36 9TirzTom, TrialTracker_MD, JennaRN and 33 others
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mike_mod
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Apr 8, 2025 at 5:35 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Thread quality here is what the rules are for. Keep it up.

37 10PurityPaulOR, MaxMetOK, MounjBrad and 34 others
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