PeptideChemSF said:Agreed, and the size of the effect matters as much as its existence.
This matches mine closely enough to be worth saying so out loud. I had assumed I was the exception until I read this.
PeptideChemSF said:Agreed, and the size of the effect matters as much as its existence.
There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.
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Browse GL BiochemOne thing that is still open after PeptideChemSF’s answer:
How long did you give it before you decided it was working?
wendy_avl said:Say what you would expect to see if you were wrong, before you look.
This is where I part company with the consensus forming above. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.