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ForumsSide Effects & ManagementAcid reflux/GERD worsening on GLP-1 — PPI interaction data Page 3

Acid reflux/GERD worsening on GLP-1 — PPI interaction data

Dr.GastroMayo Wed, May 27, 2026 at 7:16 PM 20 replies 733 viewsPage 3 of 4
KetoKyle
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May 28, 2026 at 12:09 PM#11
NurseAsh_DET said:
The practical protocol is dull and it works: smaller meals, stop eating at the first sign of fullness rather than at the end of the plate, drop the…

Genuinely useful, thank you. I had the facts and not the framework.

31 4laura_annarbor, JenMemphis, pat_auckland and 28 others
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newstart_MO
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May 28, 2026 at 2:31 PM#12

Clinical perspective, offered as context rather than as advice. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

Last edited: May 28, 2026 at 8:31 PM
32 5LibrarianMeg, bri_stats, pete_manc_UK and 29 others
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LabKate
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May 28, 2026 at 4:53 PM#13
Dr.RaviCardio said:
The mechanism and the magnitude are separate questions.

I read this differently from Dr.RaviCardio, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

Last edited: May 28, 2026 at 7:53 PM
33 6Dr.SleepRoch, laura_annarbor, JenMemphis and 30 others
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quinn_sf
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May 28, 2026 at 7:14 PM#14

Adding the numbers, since they settle part of this. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

That is the short version; the long version is somebody else's post.

Last edited: May 29, 2026 at 1:14 AM
34 7andrew_nyc, Dr.EndoEP, GraceAZ_72 and 31 others
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Admin
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May 28, 2026 at 9:35 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Tagging this one for the weekly digest.

35 8PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 32 others
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