jim_asheville said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.
WendyG_ATL said:The pharmacokinetics explain nearly every practical question asked here.
Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.
jim_asheville said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Pushing back on jim_asheville here. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.
Happy to go further on any of that.
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Browse GL BiochemThe figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.