Dr.MetabolicMD said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.
julia.endo said:The mechanism is more central than most summaries suggest.
That reframing is the part I needed. I will report back once I have actually tried it.
Dr.MetabolicMD said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
This is where I part company with the consensus forming above. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.
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Browse GL BiochemAdding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
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