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ForumsExercise & Body CompositionReturn to running after weight loss — my results so far Page 6

Return to running after weight loss — my results so far

Dr.GastroMayo Thu, Feb 19, 2026 at 3:53 AM 28 replies 1,092 viewsPage 6 of 6
NeuroNate
Senior Member
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Dec 2023
Chicago, IL
Mar 28, 2026 at 3:17 AM#26
TrialTracker_MD said:
Regarding lean mass: I accidentally injected my dose intramuscularly instead of subcutaneously last week (went in at wrong angle, too deep).

My endo's protocol for lean mass plateau: if weight loss stalls for 6+ weeks at current dose, we go through this checklist before titrating up:

  1. Food diary review — is intake creeping up?
  2. Protein check — minimum 100g/day
  3. Activity audit — steps + resistance training
  4. Sleep quality — poor sleep kills GLP-1 efficacy
  5. Stress/cortisol management

Only after addressing all of these do we increase the dose. Often fixing one lifestyle factor restarts progress without needing more medication.

31 4jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 28 others
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SleepDoc_PDX
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Sep 2024
Portland, OR
Apr 1, 2026 at 1:56 PM#27
TrialTracker_MD said:
Regarding lean mass: I accidentally injected my dose intramuscularly instead of subcutaneously last week (went in at wrong angle, too deep).

That reframing is the part I needed. Taking it to my next appointment.

32 5hank_denver, carlos_SATX, sophie_paris and 29 others
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NurseAsh_DET
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Detroit, MI
Apr 6, 2026 at 12:32 AM#28

Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Apr 6, 2026 at 6:32 AM
33 6BrianDallas92, labquiet_amy, emily_PDX and 30 others
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tammy_FL
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Nov 2024
Tampa, FL
Apr 10, 2026 at 11:05 AM#29
NurseAsh_DET said:
The mechanism and the magnitude are separate questions.

Mine went the same way, slower. Posting only so the count is not one.

34 7Dr.PainCLE, mike_mealprep, NicoleRaleigh and 31 others
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Dr.GastroMayo
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Mayo Clinic, MN
Apr 14, 2026 at 9:36 PM#30

Reporting back.

Coming back a few months on. It held. Nothing dramatic to report, which is the report.

Last edited: Apr 15, 2026 at 2:36 AM
6 4InsuranceTom, WendyG_ATL, SaraMom3 and 3 others
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