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ForumsOther Peptides & Research CompoundsHas anyone dealt with bpc-157 systemic vs local effects? Page 3

Has anyone dealt with bpc-157 systemic vs local effects?

Dr.NateNeph Thu, Aug 7, 2025 at 4:29 PM 11 replies 1,342 viewsPage 3 of 3
LarryQC_SD
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Aug 11, 2025 at 6:09 AM#11
Dr.LipidDallas said:
PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.

Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Last edited: Aug 11, 2025 at 7:09 AM
28 1NurseKim_ATL, paul_denver, TinaHashiRN and 25 others
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PedsEndoPhilly
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Philadelphia, PA
Aug 12, 2025 at 12:29 AM#12
Dr.PathRoch said:
The mechanism is more central than most summaries suggest.

Genuinely useful, thank you. I had the facts and not the framework.

Last edited: Aug 12, 2025 at 5:29 AM
29 2wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 26 others
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nancy_portland
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Aug 12, 2025 at 6:48 PM#13
Dr.LipidDallas said:
PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.

Pushing back on Dr.LipidDallas here. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

Last edited: Aug 12, 2025 at 7:48 PM
30 3MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 27 others
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jason_paloalto
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Aug 13, 2025 at 1:07 PM#14

The figures, for anyone assembling their own picture. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

I would rather be corrected than agreed with, if it comes to it.

31 4andrew_nyc, Dr.EndoEP, GraceAZ_72 and 28 others
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mike_mod
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Aug 14, 2025 at 7:26 AM#15

Moderator note: a couple of off-topic posts removed. Report rather than reply if it drifts again.

32 5PurityPaulOR, MaxMetOK, MounjBrad and 29 others
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