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ForumsMASH / Liver DiseaseWhat even is MASH? My doc mentioned it and I panicked Page 3

What even is MASH? My doc mentioned it and I panicked

nick_newbie Sun, May 17, 2026 at 1:44 AM 11 replies 492 viewsPage 3 of 3
DanielChem_CHI
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May 23, 2026 at 8:01 AM#11
Dr.EndoEP said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.

Last edited: May 23, 2026 at 10:01 AM
27 0fiona_VT, denise_HTX, raj_cambridge and 24 others
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KristenIndy
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May 25, 2026 at 12:38 PM#12
VanRx_Mike said:
Liver enzyme update related to liver and MASH: I had mildly elevated ALT/AST at baseline (likely NAFLD).

Genuinely useful, thank you. I had the facts and not the framework. I will report back once I have actually tried it.

28 1amsterdam_pete, LondonLisa, mike_nyc and 25 others
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mark_tokyo
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May 27, 2026 at 5:14 PM#13
Dr.EndoEP said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Pushing back on Dr.EndoEP here. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

Ask again with the specifics and you will get a better answer than this one.

29 2LibrarianMeg, bri_stats, pete_manc_UK and 26 others
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bri_stats
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May 29, 2026 at 9:49 PM#14

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Happy to go further on any of that.

30 3JessicaM_2024, TomFromTexas, mike.trainer_LA and 27 others
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mike_mod
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Jun 1, 2026 at 2:23 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Report rather than reply if it drifts again.

31 4PurityPaulOR, MaxMetOK, MounjBrad and 28 others
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