Retatrutide cholesterol effects — 6 month update

Dr.SurgeonPGH said:

Comprehensive lipid panel update relevant to the lipid panel: Marker Baseline 6 Months 12 Months Reference Total Cholesterol 251 196 176 <200 LDL…

Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data:

Every single metabolic marker improved. This is why I'm a believer in this therapy.

DanielChem_CHI said:

Fair, but phase 2 tolerability figures rarely survive contact with phase 3 scale.

This answered a question I did not know how to ask. Sending this to two other people who asked me the same thing last week.

Dr.SurgeonPGH said:

Comprehensive lipid panel update relevant to the lipid panel: Marker Baseline 6 Months 12 Months Reference Total Cholesterol 251 196 176 <200 LDL…

I would rather people stopped quoting the 24% as if it were a licensed outcome. It is a phase 2 result in a few hundred participants with no cardiovascular endpoint and no long-term safety data, and this board has a habit of treating pipeline numbers as settled.

DerekSJ_a1c said:

Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.

Advanced lipoprotein testing on the lipid panel — going beyond standard lipid panel:

The shift from small dense to large buoyant LDL is particularly important — it represents a fundamental change in the atherogenic profile.

Moderator note: a couple of off-topic posts removed.