One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.
Happy to go further on any of that.
One thing that is still open after Dr.EM_Chicago’s answer:
Why adding glucagon agonism to an anti-obesity drug is not self-defeating, given that glucagon raises blood glucose?
dave_SLC said:One practical note: write down what you did and when, before you need it.
Coming at dave_SLC’s question from a different direction. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
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Browse GL BiochemClosing the loop on my own question.
Rereading it with the dropout table open changed my view. I still think it is the most interesting molecule in the pipeline; I no longer think the 24% is the number that will end up on a label.
VanRx_Mike said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.