Retatrutide Phase 2 dose-response analysis — need advice

Following on from chris_chi24 — and this may be the naive question:

Was that from a primary source or from a summary of one?

raj_cambridge said:

For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

This is where I part company with the consensus forming above. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Carry on.

raj_cambridge said:

For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.

Adding the clinical framing, because it changes how the question reads. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.