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ForumsRetatrutide & Triple AgonistsBeen on the reta waiting list for months - anyone heard anything? — 6 month update Page 2

Been on the reta waiting list for months - anyone heard anything? — 6 month update

hannah_MT Sun, Oct 12, 2025 at 4:28 PM 11 replies 1,308 viewsPage 2 of 3
Dr.PainCLE
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Oct 12, 2025 at 7:38 PM#6
PeptideChemSF said:
The version of this that has an answer is narrower than the version being asked.

I would rather people stopped quoting the 24% as if it were a licensed outcome. It is a phase 2 result in a few hundred participants with no cardiovascular endpoint and no long-term safety data, and this board has a habit of treating pipeline numbers as settled.

6 1Dr.PathRoch, mona_PHX, andrew_nyc and 3 others
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kate.chem
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Oct 12, 2025 at 8:53 PM#7

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Last edited: Oct 12, 2025 at 11:53 PM
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LipidDoc_ATL
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Oct 12, 2025 at 10:08 PM#8
Dr.PainCLE said:
I would rather people stopped quoting the 24% as if it were a licensed outcome.

There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Happy to go further on any of that.

Last edited: Oct 13, 2025 at 3:08 AM
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mel_PDX
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Oct 12, 2025 at 11:23 PM#9

One thing that is still open after Dr.GastroMayo’s answer:

Why adding glucagon agonism to an anti-obesity drug is not self-defeating, given that glucagon raises blood glucose?

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hannah_MT
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Oct 13, 2025 at 5:21 AM#10

OP back with an update, since a thread like this is useless without one.

Rereading it with the dropout table open changed my view. I still think it is the most interesting molecule in the pipeline; I no longer think the 24% is the number that will end up on a label.

Last edited: Oct 13, 2025 at 8:21 AM
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