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ForumsCardiovascular OutcomesHas anyone dealt with coronary artery calcium score changes on glp-1? Page 7

Has anyone dealt with coronary artery calcium score changes on glp-1?

KarenAZ_mom Thu, Apr 4, 2024 at 11:16 PM 35 replies 2,233 viewsPage 7 of 7
DadBodDave
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Nov 2024
Ohio
Apr 11, 2024 at 5:04 AM#31
KarenAZ_mom said:
Dizziness and cardiovascular risk: I was lightheaded for the first 2 weeks.

Cardiac biomarkers and cardiovascular risk: my cardiologist ordered advanced cardiac labs given my family history. Results were encouraging:

  • NT-proBNP: 64 pg/mL (normal, cardiac function preserved)
  • Lp(a): 34 nmol/L (genetic, unchanged — expected)
  • ApoB: dropped from 159 to 89 mg/dL (excellent response)
  • Coronary calcium score: 0 (unchanged from baseline — reassuring)

The ApoB reduction is particularly meaningful — it's considered the best single predictor of cardiovascular risk. GLP-1 therapy seems to improve this consistently.

Last edited: Apr 11, 2024 at 8:04 AM
47 20laura_annarbor, JenMemphis, pat_auckland and 44 others
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NicoleRaleigh
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Aug 2024
Raleigh, NC
Apr 11, 2024 at 3:40 PM#32
KarenAZ_mom said:
Dizziness and cardiovascular risk: I was lightheaded for the first 2 weeks.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

Ask again with the specifics and you will get a better answer than this one.

48 21MikeFit_NJ, InsuranceTom, WendyG_ATL and 45 others
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amy_econ_NJ
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May 2024
Princeton, NJ
Apr 12, 2024 at 2:16 AM#33
KarenAZ_mom said:
Dizziness and cardiovascular risk: I was lightheaded for the first 2 weeks.

Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.

49 22sean_dublin, hannah_MT, Dr.SportsMedIN and 46 others
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claudia_zurich
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Zurich, CH
Apr 12, 2024 at 12:51 PM#34

From the other side of the consultation, briefly. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

50 23alex_tucson, kevin_tulsa, Dr.PainCLE and 47 others
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anders_CPH
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Feb 2024
Copenhagen, DK
Apr 12, 2024 at 11:26 PM#35
claudia_zurich said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Mine went the same way, slower.

1 24ChrisMacros
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