🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesApoB reduction on tirzepatide — looking for input Page 5

ApoB reduction on tirzepatide — looking for input

TomTeleRx Tue, Jul 9, 2024 at 9:38 AM 34 replies 2,140 viewsPage 5 of 7
pete_manc_UK
Senior Member
1,234
5,678
Mar 2024
Manchester, UK
Jul 11, 2024 at 3:23 PM#21
TomFromTexas said:
True, with the qualification that this is a self-selected group.

This is my experience too, for whatever a second data point is worth.

4 2TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 1 other
Reply Quote Save Share Report
Dr.SportsMedIN
Senior Member
1,456
6,789
Feb 2024
Indianapolis, IN
Jul 11, 2024 at 11:41 PM#22
TomFromTexas said:
True, with the qualification that this is a self-selected group.

Adding the part of the answer the thread has not reached. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

5 3lisa_labSD, adam_van, Dr.SurgeonPGH and 2 others
Reply Quote Save Share Report
quinn_sf
Member
489
2,123
Jun 2024
San Francisco, CA
Jul 12, 2024 at 7:59 AM#23

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Happy to go further on any of that.

6 4mona_PHX, andrew_nyc, Dr.EndoEP and 3 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
chris_chi24
Member
389
1,678
Sep 2024
Chicago, IL
Jul 12, 2024 at 4:17 PM#24

One thing that is still open after TomFromTexas’s answer:

Whether an unchanged LDL-C alongside a large triglyceride fall is a good result or a bad one, because ApoB and LDL-C seem to be telling different stories?

Last edited: Jul 12, 2024 at 7:17 PM
7 5PurityPaulOR, MaxMetOK, MounjBrad and 4 others
Reply Quote Save Share Report
Dr.EM_Chicago
Member
567
2,567
May 2024
Chicago, IL
Jul 13, 2024 at 12:35 AM#25
quinn_sf said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

I read this differently from quinn_sf, on substance rather than tone. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

Happy to go further on any of that.

Last edited: Jul 13, 2024 at 4:35 AM
8 6lisa_labSD, adam_van, Dr.SurgeonPGH and 5 others
Reply Quote Save Share Report

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register