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ForumsCardiovascular OutcomesSOUL trial preliminary data — November 2025 Page 3

SOUL trial preliminary data — November 2025

JenMemphis Sun, Mar 16, 2025 at 2:50 AM 51 replies 2,130 viewsPage 3 of 11
Dr.AddMedPHL
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Mar 18, 2025 at 3:05 PM#11
newstart_MO said:
Forest plot interpretation for the the trial evidence meta-analysis: when reading the pooled estimate, pay attention to: Point estimate (HR/RR/OR) —…

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

Last edited: Mar 18, 2025 at 5:05 PM
23 21FitDadDave, RunnerRach, TrialNerd_Beth and 20 others
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GenomicsKate
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Mar 18, 2025 at 8:58 PM#12
A1cHero_PHX said:
BariatricNurseD said: ...regarding the trial evidence...

That reframing is the part I needed. I will report back once I have actually tried it.

24 22KristenIndy, MarkLI_maint, Dr.PeteFamMed and 21 others
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MASHdoc_SA
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Mar 19, 2025 at 2:51 AM#13
newstart_MO said:
Forest plot interpretation for the the trial evidence meta-analysis: when reading the pooled estimate, pay attention to: Point estimate (HR/RR/OR) —…

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

Last edited: Mar 19, 2025 at 5:51 AM
25 23JennaRN, LabKate, kate.chem and 22 others
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labquiet_amy
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Mar 19, 2025 at 8:44 AM#14

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

I would rather be corrected than agreed with, if it comes to it.

26 24bri_stats, pete_manc_UK, anna.melb_AU and 23 others
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mike_mod
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Mar 19, 2025 at 2:37 PM#15

Moderator note: a couple of off-topic posts removed. Carry on.

27 0PurityPaulOR, MaxMetOK, MounjBrad and 24 others
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