Has anyone dealt with surmount-2: tirzepatide for t2dm + obesity?

A narrower follow-up, since the general answer is now clear:

How long did you give it before you decided it was working?

PharmacoVig_BOS said:

If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Pushing back on PharmacoVig_BOS here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

I would rather be corrected than agreed with, if it comes to it.

PharmacoVig_BOS said:

If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

PharmacoVig_BOS said:

If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Saving this. It is the first explanation that did not require me to already understand it.

OP back with an update, since a thread like this is useless without one.

Closing this out. What actually changed my mind was the point about waiting for a trend instead of reading a single measurement, which is embarrassing in hindsight and worth saying anyway.