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ForumsCompounding & FormulationMy vial looks cloudy - throw it out?? — looking for input Page 3

My vial looks cloudy - throw it out?? — looking for input

SleepFixSam Thu, Mar 21, 2024 at 7:19 PM 30 replies 2,350 viewsPage 3 of 6
jennifer_SEA
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Mar 22, 2024 at 7:28 PM#11
VanRx_Mike said:
Resolution therefore closed the doors unevenly, and the asymmetry follows from the bulks lists.

Saving this. It is the first explanation that did not require me to already understand it.

Last edited: Mar 23, 2024 at 1:28 AM
39 12lucas_SP_BR, lisa_labSD, adam_van and 36 others
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paige_pharma
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Mar 23, 2024 at 5:08 AM#12

Adding the clinical framing, because it changes how the question reads.

Compounding pharmacy customer here with experience relevant to compounded supply.

I've ordered from 5 different compounding pharmacies over the past 18 months. The quality variation is real — purity ranged from 94% to 101% of label claim based on independent Janoshik testing.

My current compounder (a 503B facility) has been consistently 98-101% purity across 5 orders. I pay $124/month vs $1,334 for brand. The savings are substantial and the product is equivalent in my experience.

Re: compounded supply — this applies whether you're using brand or compounded. The clinical principles are the same.

40 13Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 37 others
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sarah.morrison
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Mar 23, 2024 at 2:48 PM#13
Dr.DermMIA said:
Price comparison for compounded supply across sources I've used: Source Monthly Cost Type Purity Verified Brand (Ozempic) $1057 FDA-approved N/A…

Beyond-use dating (BUD) for compounded supply compounded products:

Lyophilized (unreconstituted): typically 9 months from compounding date
Reconstituted with BAC water: typically 28-30 days refrigerated
Reconstituted with sterile water: typically 7 days (no preservative!)

Always use BAC water for multi-dose vials. Sterile water has no preservative and supports bacterial growth after first puncture. This is a common and potentially dangerous mistake.

Last edited: Mar 23, 2024 at 3:48 PM
41 14tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 38 others
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quinn_sf
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Mar 24, 2024 at 12:28 AM#14
SleepFixSam said:
The shortage clause is the answer to the second question and it is a subtraction rather than an addition.

Vendor communication red flags for compounded supply:

  • Won't provide COA before purchase — walk away
  • Claims "100% pure" without analytical data — unrealistic
  • No physical address or phone number — accountability matters
  • Pushes you to buy more than you need — pressure tactics
  • Won't answer questions about their compounding process — transparency is key
  • Payment only via crypto or wire transfer — legitimate pharmacies accept cards

A legitimate compounding pharmacy operates like a healthcare business, not a gray market dealer.

42 15andrew_nyc, Dr.EndoEP, GraceAZ_72 and 39 others
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mike_mod
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Mar 24, 2024 at 10:08 AM#15

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here.

Last edited: Mar 24, 2024 at 12:08 PM
43 16PurityPaulOR, MaxMetOK, MounjBrad and 40 others
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