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ForumsCompounding & FormulationHas anyone dealt with dumb question - what is bacteriostatic water exactly? Page 3

Has anyone dealt with dumb question - what is bacteriostatic water exactly?

NauseaFreeNow Thu, Apr 4, 2024 at 10:28 PM 49 replies 2,765 viewsPage 3 of 10
DataDave
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Apr 9, 2024 at 7:06 PM#11
NurseLeah_Nash said:
Regarding dosing arithmetic multi-dose vial contamination prevention: after reconstituting, I wipe the vial stopper with a fresh alcohol swab before…

Reconstitution tip for anyone mixing dosing arithmetic from lyophilized powder: use bacteriostatic water, NOT sterile water. The benzyl alcohol in BAC water preserves multi-dose vials for up to 28 days.

Inject the water slowly down the side of the vial. NEVER shake — gentle swirling only until fully dissolved. Should be crystal clear with no particles.

Last edited: Apr 9, 2024 at 8:06 PM
44 17VendorMark, COA_Karl, MikeFit_NJ and 41 others
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ingrid_STO
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Apr 12, 2024 at 10:50 AM#12
ben_calgary said:
The arithmetic is right and one caveat matters: a U-40 syringe changes the markings, not the volumes.

This is exactly what I could not find anywhere else. I will report back once I have actually tried it.

45 18COA_Karl, MikeFit_NJ, InsuranceTom and 42 others
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kevin_tulsa
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Apr 15, 2024 at 2:36 AM#13
NurseLeah_Nash said:
Regarding dosing arithmetic multi-dose vial contamination prevention: after reconstituting, I wipe the vial stopper with a fresh alcohol swab before…

Quick syringe math for dosing arithmetic dosing: if your vial is reconstituted at 5mg/2mL, that's 2.5mg/mL. For a 0.25mg dose you need 0.1mL = 10 units on an insulin syringe.

I keep a chart on my fridge:

  • 0.25mg = 10 units
  • 0.5mg = 20 units
  • 1.0mg = 40 units
  • 1.25mg = 50 units

Always double-check your concentration before drawing up!

46 19greg_boulder, quinn_sf, NurseLeah_Nash and 43 others
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dan_philly
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Apr 17, 2024 at 6:23 PM#14
NauseaFreeNow said:
Two of us with identical vials and identical diluent arrived at different unit counts, which means one of us has a conceptual error rather than a…

For anyone reconstituting dosing arithmetic peptides: the water-to-powder ratio determines your concentration. Here's my reference:

Vial SizeBAC WaterConcentration0.25mg Dose
5mg2mL2.5mg/mL10 units
5mg2.5mL2mg/mL12.5 units
10mg2mL5mg/mL5 units
10mg3mL3.33mg/mL7.5 units

More water = easier to measure small doses but vial runs out faster. Find the balance that works for your dose.

Last edited: Apr 17, 2024 at 9:23 PM
47 20Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 44 others
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mike_mod
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Apr 20, 2024 at 10:12 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.

48 21PurityPaulOR, MaxMetOK, MounjBrad and 45 others
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