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ForumsCardiovascular OutcomesHas anyone dealt with apob reduction on tirzepatide? Page 8

Has anyone dealt with apob reduction on tirzepatide?

tampaLisa73 Sat, Apr 26, 2025 at 11:05 AM 41 replies 2,416 viewsPage 8 of 9
Dr.PainCLE
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Oct 7, 2025 at 12:20 PM#36
jason_paloalto said:
One practical note: write down what you did and when, before you need it.

Genuinely useful, thank you. I had the facts and not the framework. Printing the relevant bit and taking it with me.

23 21Dr.PathRoch, mona_PHX, andrew_nyc and 20 others
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Dr.ReproEndo
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Oct 16, 2025 at 8:43 PM#37

From the other side of the consultation, briefly. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Last edited: Oct 16, 2025 at 9:43 PM
24 22andrew_nyc, Dr.EndoEP, GraceAZ_72 and 21 others
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rick_sfbay
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Oct 26, 2025 at 5:12 AM#38
Dr.ReproEndo said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

This is my experience too, for whatever a second data point is worth. I had assumed I was the exception until I read this.

25 23james_edin, FranDenver, Dr.BariatricHTX and 22 others
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BariatricNurseD
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Nov 4, 2025 at 1:46 PM#39
Dr.ReproEndo said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Adding the part of the answer the thread has not reached. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

Last edited: Nov 4, 2025 at 6:46 PM
26 24tom_AK, josh_phd_bmore, roxy_nash and 23 others
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Dr.PathRoch
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Nov 13, 2025 at 10:25 PM#40

One concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

48 21Dr.MetabolicMD, RetaRick_CA, JenPlateau and 45 others
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