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ForumsCardiovascular OutcomesHas anyone dealt with apob reduction on tirzepatide? Page 3

Has anyone dealt with apob reduction on tirzepatide?

tampaLisa73 Sat, Apr 26, 2025 at 11:05 AM 41 replies 2,416 viewsPage 3 of 9
BariatricNurseD
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Apr 30, 2025 at 10:26 PM#11
carl_compliance said:
ApoB is the more informative number and it is cheap.

Agreed, and hsCRP is worth reading alongside them. The inflammatory-marker fall is often the most striking change on a panel and it is consistent with the cardiovascular outcome data.

That is the short version; the long version is somebody else's post.

Last edited: May 1, 2025 at 3:26 AM
6 4tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 3 others
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cory_ATX
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May 2, 2025 at 11:30 PM#12
amsterdam_pete said:
Agreed on the mechanism, with the caveat that the head-to-head used semaglutide 1mg, not 2.4mg.

Bookmarking. The distinction being drawn above is the one nobody else makes. Taking it to my next appointment.

7 5andrew_nyc, Dr.EndoEP, GraceAZ_72 and 4 others
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wanda_boise
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May 5, 2025 at 12:35 AM#13
carl_compliance said:
ApoB is the more informative number and it is cheap.

Careful with treating an unchanged LDL-C as a failure. If ApoB and triglycerides both fell, the particle picture improved regardless of what the calculated LDL says.

Worth separating that from the lipid panel, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

8 6pam_columbus, nick_SD_fit, ben_calgary and 5 others
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SleepDoc_PDX
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May 7, 2025 at 1:41 AM#14

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

9 7sophie_paris, mel_PDX, Dr.AddMedPHL and 6 others
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mike_mod
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May 9, 2025 at 2:48 AM#15

Moderator note: a couple of off-topic posts removed. Thread quality here is what the rules are for. Keep it up.

10 8PurityPaulOR, MaxMetOK, MounjBrad and 7 others
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