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ForumsClinical Trials & ResearchPhase 3 trial enrollment guide — my results so far Page 3

Phase 3 trial enrollment guide — my results so far

josh_phd_bmore Mon, Feb 23, 2026 at 12:22 PM 21 replies 1,019 viewsPage 3 of 5
Dr.CardioMD
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Feb 26, 2026 at 3:24 AM#11
roxy_nash said:
Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

31 6kim_atl_prep, sarah_TO, wendy_avl and 28 others
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tampaLisa73
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Feb 26, 2026 at 10:25 AM#12
LarryQC_SD said:
Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…

This is exactly what I could not find anywhere else. Taking it to my next appointment.

30 5FitDadDave, RunnerRach, TrialNerd_Beth and 27 others
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GraceAZ_72
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Feb 26, 2026 at 5:27 PM#13
roxy_nash said:
Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

29 4SallyK_inj, CryptoCarl, MariaRD and 26 others
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jason_paloalto
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Feb 27, 2026 at 12:29 AM#14

The figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Feb 27, 2026 at 5:29 AM
28 3andrew_nyc, Dr.EndoEP, GraceAZ_72 and 25 others
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Admin
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Feb 27, 2026 at 7:31 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Report rather than reply if it drifts again.

Last edited: Feb 27, 2026 at 11:31 AM
27 2PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 24 others
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