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ForumsCardiovascular OutcomesMy dad had a heart attack and now I am terrified - will GLP-1 help? — looking for input Page 7

My dad had a heart attack and now I am terrified - will GLP-1 help? — looking for input

PharmHunterJen Thu, Jul 3, 2025 at 12:34 AM 37 replies 2,232 viewsPage 7 of 8
BariatricNurseD
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Jul 22, 2025 at 5:04 PM#31

From the other side of the consultation, briefly.

Metabolic syndrome resolution on cardiovascular risk: I went from meeting 3 of 5 diagnostic criteria to meeting ZERO after 11 months of treatment.

The 5 criteria (and my journey):

  1. Waist circumference: 50" → 36" ✅ Resolved
  2. Triglycerides: 270 → 95 ✅ Resolved
  3. HDL: 34 → 52 ✅ Resolved
  4. Blood pressure: 140/92 → 118/72 ✅ Resolved
  5. Fasting glucose: 120 → 86 ✅ Resolved

Metabolic syndrome reversal is, in my view, the most medically significant outcome of GLP-1 therapy.

34 9tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 31 others
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lori_vegas
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Jul 24, 2025 at 3:43 AM#32
BariatricNurseD said:
Metabolic syndrome resolution on cardiovascular risk: I went from meeting 3 of 5 diagnostic criteria to meeting ZERO after 11 months of treatment.

Mine went the same way, slower. The detail I would add is minor and it is already implied above.

33 8bbq_ray_KC, oliver_london, tane_welly and 30 others
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SleepFixSam
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Hawaii
Jul 25, 2025 at 2:21 PM#33
BariatricNurseD said:
Metabolic syndrome resolution on cardiovascular risk: I went from meeting 3 of 5 diagnostic criteria to meeting ZERO after 11 months of treatment.

Coming at BariatricNurseD’s question from a different direction. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

32 7raj_cambridge, ingrid_STO, pete_nash and 29 others
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bri_stats
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Jul 27, 2025 at 12:58 AM#34

The figures, for anyone assembling their own picture. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

I would rather be corrected than agreed with, if it comes to it.

31 6JessicaM_2024, TomFromTexas, mike.trainer_LA and 28 others
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Dr.GutHealth
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Jul 28, 2025 at 11:34 AM#35

One thing that is still open after BariatricNurseD’s answer:

How would you tell the difference between that and the alternative explanation?

30 5MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 27 others
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