CagriSema (amylin + semaglutide) — my results so far

Dr.NateNeph said:

For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and…

I read this differently from Dr.NateNeph, on substance rather than tone. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

I would rather be corrected than agreed with, if it comes to it.

Dr.NateNeph said:

For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and…

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

Dr.NateNeph said:

For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and…

Saving this. It is the first explanation that did not require me to already understand it. Adding it to my notes with a link back to this thread.

Adding the clinical framing, because it changes how the question reads. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Closing the loop on my own question.

Six weeks on from posting: I stopped reading the weekly number and started reading a four-week average, and the "stall" I opened this thread about was a 1.8kg loss I could not see.