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ForumsClinical Trials & ResearchOrforglipron ATTAIN-4 — cardiovascular outcomes arm Page 4

Orforglipron ATTAIN-4 — cardiovascular outcomes arm

TrialTracker_MD Mon, May 25, 2026 at 7:53 AM 21 replies 544 viewsPage 4 of 5
TirzTom
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May 28, 2026 at 1:10 PM#16
CarlaRPh_TPA said:
Start from the measurement rather than the conclusion.

This matches mine closely enough to be worth saying so out loud. I had assumed I was the exception until I read this.

27 2josh_phd_bmore, roxy_nash, tony_orlando and 24 others
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josh_phd_bmore
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May 29, 2026 at 12:45 AM#17
Dr.RaviCardio said:
Practical: whatever you change, write down the date and the reason.

There is a second half to this that has not been said yet. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Last edited: May 29, 2026 at 2:45 AM
26 1Dr.ObesityLA, NurseKim_ATL, paul_denver and 23 others
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DoseLogDan
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May 29, 2026 at 12:20 PM#18

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

25 0mel_PDX, Dr.AddMedPHL, newstart_MO and 22 others
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tane_welly
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May 29, 2026 at 11:56 PM#19

One thing that is still open after Dr.RaviCardio’s answer:

How long did you give it before you decided it was working?

Last edited: May 30, 2026 at 2:56 AM
24 24marco_milano, pam_columbus, nick_SD_fit and 21 others
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mike_mod
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May 30, 2026 at 11:31 AM#20

Moderator note: the sourcing question belongs in the vendor section and has been split out. Tagging this one for the weekly digest.

2 2PurityPaulOR, MaxMetOK
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