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ForumsCompounding & FormulationNeedle gauge and dead space — March 2026 Page 6

Needle gauge and dead space — March 2026

TirzTom Wed, Jun 4, 2025 at 6:46 PM 49 replies 2,557 viewsPage 6 of 10
matt_MKE
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Jun 16, 2025 at 6:49 AM#26
wendy_avl said:
Quick syringe math for dosing arithmetic dosing: if your vial is reconstituted at 5mg/2mL, that's 2.5mg/mL.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

18 18andrew_nyc, Dr.EndoEP, GraceAZ_72 and 15 others
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marcus_mpls
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Jun 17, 2025 at 3:01 PM#27
wendy_avl said:
Quick syringe math for dosing arithmetic dosing: if your vial is reconstituted at 5mg/2mL, that's 2.5mg/mL.

That is correct as far as it goes, and here is where it stops going. Yes, and the corollary is less popular: if the reasoning holds, it also holds where it produces an answer we do not like.

17 17oliver_london, tane_welly, Dr.PathRoch and 14 others
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nancy_portland
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Jun 18, 2025 at 11:14 PM#28
wendy_avl said:
Quick syringe math for dosing arithmetic dosing: if your vial is reconstituted at 5mg/2mL, that's 2.5mg/mL.

This is exactly what I could not find anywhere else. Printing the relevant bit and taking it with me.

16 16MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 13 others
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Dr.SleepRoch
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Jun 20, 2025 at 7:28 AM#29

Adding the clinical framing, because it changes how the question reads. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

15 15tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 12 others
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TirzTom
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Jun 21, 2025 at 3:42 PM#30

Reporting back.

Resolved, and the thing that resolved it was the least interesting suggestion in the thread. Writing that down for the next person who wants the interesting answer.

43 18DeniseRN_TPA, SandraNC_45, Dr.EndoIndy and 40 others
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