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ForumsPublic SquareGLP-1 therapy in patients over 65 — July 2024 Page 2

GLP-1 therapy in patients over 65 — July 2024

andrew_nyc Sun, Apr 6, 2025 at 4:10 AM 9 replies 1,617 viewsPage 2 of 2
FDA_TrackerJim
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Rockville, MD
Apr 6, 2025 at 8:32 PM#6
andrew_nyc said:
The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.

Body image adjustment with mental health: I've lost 69 lbs but when I look in the mirror, I still see my old self sometimes. "Phantom fat" is a real phenomenon.

My therapist specializes in body image issues with weight loss patients. She says it can take 12-18 months for your brain's body map to update. In the meantime: take progress photos (your eyes lie but cameras don't), try on old clothes, and be patient with yourself.

45 23Dr.Martinez, mike_mod, SarahChen_PharmD and 42 others
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newstart_MO
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Springfield, MO
Apr 7, 2025 at 3:01 AM#7

One thing that is still open after LipidDoc_ATL’s answer:

How long did you give it before you decided it was working?

Last edited: Apr 7, 2025 at 9:01 AM
46 24LibrarianMeg, bri_stats, pete_manc_UK and 43 others
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Dr.BariatricHTX
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Apr 7, 2025 at 9:30 AM#8
FDA_TrackerJim said:
Body image adjustment with mental health: I've lost 69 lbs but when I look in the mirror, I still see my old self sometimes.

When to call your doctor about mental health side effects — a reference I wish I'd had:

Call immediately:

  • Severe abdominal pain (could be pancreatitis)
  • Vision changes (thyroid concern)
  • Lump in neck (thyroid nodule)
  • Severe vomiting/can't keep fluids down for 24h+

Schedule an appointment:

  • Persistent nausea beyond 4 weeks
  • Significant hair loss
  • Mood changes or depression
  • Gallbladder symptoms (RUQ pain after eating)
47 0Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 44 others
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andrew_nyc
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Apr 7, 2025 at 3:59 PM#9

Closing the loop on my own question.

Update: I got the sleep and the intake sorted before deciding it was the drug, and most of the flatness went with them. Not all of it, and I am watching the rest.

48 1julia.endo, JessicaM_2024, TomFromTexas and 45 others
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AttorneyGrant
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Apr 8, 2025 at 11:08 PM#10
Dr.BariatricHTX said:
When to call your doctor about mental health side effects — a reference I wish I'd had: Call immediately: Severe abdominal pain (could be…

One year anniversary on mental health — reflections:

What I wish I'd known: the side effects are temporary, the benefits compound over time, protein is more important than I thought, and the mental health aspect needs as much attention as the physical.

What surprised me: how much my relationship with food changed, the cascade of health improvements beyond weight, and how supportive this community is.

What I'd do differently: start therapy earlier, prioritize resistance training from day 1, and stop comparing my progress to others. Everyone's journey is unique.

8 6Dr.GastroMayo, JakeBK_lifts, DerekSJ_a1c and 5 others
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