I was on CPAP before starting and my most recent study came back changed enough that the conversation about it is now a different conversation.
What I actually want to know is what people did about re-titration, because feeling better is not the same as a study saying you are better.
Tell me what I have not thought of.
Answering the narrow version, because the broad one does not have a single answer. Steady state is faster than people expect: half-life about five days, so you are at plateau in roughly three to four weeks rather than five. That matters when you are deciding whether a dose step has finished expressing itself.
Dr.SleepRoch said:Steady state is faster than people expect: half-life about five days, so you are at plateau in roughly three to four weeks rather than five.
True, though the ladder is longer and that is not a neutral detail — six dose steps means six opportunities to stall on the way up, and plenty of people never reach the dose the headline number came from.
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View ResultsBariatricNurseD said:I was on CPAP before starting and my most recent study came back changed enough that the conversation about it is now a different conversation.
Agreed on the mechanism, with the caveat that the head-to-head used semaglutide 1mg, not 2.4mg. It is still the best direct evidence available, but it is not the comparison most people think they are citing.
Ask again with the specifics and you will get a better answer than this one.
From the other side of the consultation, briefly.
Sleep changes on sleep apnoea: anyone else sleeping differently? I've been sleeping more deeply since starting week 4.
My theory: the weight loss has improved my sleep apnea (confirmed by recent sleep study — AHI dropped from 32 to 3). Better oxygenation at night = better sleep quality = more energy during the day. It's a virtuous cycle.