ClinicalTrials.gov GLP-1 trial tracker — updated weekly

Following on from NurseKim_ATL — and this may be the naive question:

How long did you give it before you decided it was working?

LabKate said:

If you are going to change something, change one thing and give it long enough to express itself.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

LabKate said:

If you are going to change something, change one thing and give it long enough to express itself.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

Ask again with the specifics and you will get a better answer than this one.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.

This was answered several pages up and is worth repeating rather than re-litigating:

I would add the less popular caveat: these trial populations under-represented several groups, older adults and the highest BMI categories among them. The results probably generalise, and "probably" should be stated as an assumption rather than dropped.