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ForumsPublic SquareCompounded sema shortage — my results so far Page 6

Compounded sema shortage — my results so far

mark_tokyo Sat, Aug 16, 2025 at 4:25 PM 32 replies 1,406 viewsPage 6 of 7
paul_denver
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3,234
May 2024
Denver, CO
Aug 20, 2025 at 1:07 AM#26
claudia_zurich said:
For compounded supply users considering compounded for the first time: here's a step-by-step guide: Get a prescription from your doctor (telehealth…

Adding a me-too, because a thread of one person's experience is not much use. Nothing to add that would improve it.

46 21Dr.LeslieOBGYN, MikeNYC_runner and 43 others
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PeptideSynthNJ
Member
234
1,234
Aug 2024
Princeton, NJ
Aug 20, 2025 at 9:10 AM#27
claudia_zurich said:
For compounded supply users considering compounded for the first time: here's a step-by-step guide: Get a prescription from your doctor (telehealth…

Price comparison for compounded supply across sources I've used:

SourceMonthly CostTypePurity Verified
Brand (Ozempic)$934FDA-approvedN/A (pharma)
503B Compounding$164cGMP compoundedYes (in-house)
503A Compounding$124Patient-specificVaries
Research peptide$49Not for human useOften Janoshik

I use the 503B option — best balance of quality, cost, and legality. The brand price is insane but insurance can help if you qualify.

45 20NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 42 others
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LabKate
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11,234
Jan 2024
Oregon
Aug 20, 2025 at 5:13 PM#28
claudia_zurich said:
For compounded supply users considering compounded for the first time: here's a step-by-step guide: Get a prescription from your doctor (telehealth…

Beyond-use dating (BUD) for compounded supply compounded products:

Lyophilized (unreconstituted): typically 6 months from compounding date
Reconstituted with BAC water: typically 28-30 days refrigerated
Reconstituted with sterile water: typically 24 hours (no preservative!)

Always use BAC water for multi-dose vials. Sterile water has no preservative and supports bacterial growth after first puncture. This is a common and potentially dangerous mistake.

Last edited: Aug 20, 2025 at 8:13 PM
44 19Dr.SleepRoch, laura_annarbor, JenMemphis and 41 others
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KarenAZ_mom
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567
2,567
Aug 2024
Scottsdale, AZ
Aug 21, 2025 at 1:16 AM#29

Following on from claudia_zurich — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

43 18LibrarianMeg, bri_stats, pete_manc_UK and 40 others
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mark_tokyo
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Jun 2024
Tokyo, JP
Aug 21, 2025 at 9:20 AM#30
LabKate said:
Beyond-use dating (BUD) for compounded supply compounded products: Lyophilized (unreconstituted): typically 6 months from compounding date…

Regarding compounded supply compounding legality: compounding pharmacies can legally produce semaglutide and tirzepatide while these drugs remain on the FDA shortage list. If/when the shortage resolves, the legal landscape may change.

Stay informed. The FDA shortage list is updated regularly. Current status as of my last check: semaglutide still in shortage, tirzepatide removed from shortage list. This directly impacts compounding availability.

21 21TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 18 others
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