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ForumsPsychological & BehavioralSleep quality changes on GLP-1 — November 2025 Page 3

Sleep quality changes on GLP-1 — November 2025

MeganSA_TX Sun, Apr 6, 2025 at 4:42 AM 12 replies 1,551 viewsPage 3 of 3
anna.melb_AU
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Apr 7, 2025 at 5:57 PM#11
andrew_nyc said:
Body image adjustment with mental health: I've lost 82 lbs but when I look in the mirror, I still see my old self sometimes.

Thank you for spelling out the reasoning rather than just the conclusion.

Last edited: Apr 7, 2025 at 9:57 PM
30 5DerekSJ_a1c, paige_pharma, emma_london and 27 others
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jim_asheville
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Apr 9, 2025 at 1:40 AM#12

Adding the clinical framing, because it changes how the question reads.

When to call your doctor about mental health side effects — a reference I wish I'd had:

Call immediately:

  • Severe abdominal pain (could be pancreatitis)
  • Vision changes (thyroid concern)
  • Lump in neck (thyroid nodule)
  • Severe vomiting/can't keep fluids down for 24h+

Schedule an appointment:

  • Persistent nausea beyond 4 weeks
  • Significant hair loss
  • Mood changes or depression
  • Gallbladder symptoms (RUQ pain after eating)
Last edited: Apr 9, 2025 at 4:40 AM
29 4BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 26 others
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DataDave
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Apr 10, 2025 at 9:22 AM#13
Dr.GutHealth said:
bri_stats said: ...mental health should only be used alongside therapy...

Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me. Change — even positive change — is stressful. I was anxious about loose skin.

This is more common than people admit. A therapist who specializes in weight management has been invaluable. Don't neglect the mental health side of this journey.

28 3LondonLisa, mike_nyc, VendorMark and 25 others
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TirzTom
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Apr 11, 2025 at 5:03 PM#14
MeganSA_TX said:
The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.

Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

I have a history of binge eating disorder. My psychiatrist, therapist, and prescribing doctor all collaborate on my care. The GLP-1 agonist has actually been therapeutic — it removes the biological urgency of binge impulses without relying on restriction.

This is NOT appropriate for all ED patients. Anorexia, bulimia, and restrictive EDs require different approaches. But for BED specifically, the evidence and my personal experience are positive. Always involve your mental health team.

27 2SandraNC_45, Dr.EndoIndy, tom_AK and 24 others
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Admin
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Apr 13, 2025 at 12:44 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.

26 1PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 23 others
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