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ForumsPublic SquareIs there a ceiling effect for GLP-1-mediated weight loss? — my results so far Page 4

Is there a ceiling effect for GLP-1-mediated weight loss? — my results so far

raj_cambridge Mon, Dec 15, 2025 at 6:20 AM 33 replies 1,411 viewsPage 4 of 7
roxy_nash
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Dec 17, 2025 at 4:24 PM#16

Adding the clinical framing, because it changes how the question reads. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

6 6josh_phd_bmore, roxy_nash, tony_orlando and 3 others
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hank_denver
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Dec 18, 2025 at 1:00 AM#17

Adding the numbers, since they settle part of this. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

Last edited: Dec 18, 2025 at 5:00 AM
5 5raj_cambridge, ingrid_STO, pete_nash and 2 others
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mark_tokyo
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Dec 18, 2025 at 9:36 AM#18

One thing that is still open after DoseLogDan’s answer:

What would you measure differently if you were starting again?

Last edited: Dec 18, 2025 at 12:36 PM
4 4LibrarianMeg, bri_stats, pete_manc_UK and 1 other
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stefan_berlin
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Dec 18, 2025 at 6:12 PM#19
hank_denver said:
Keep the original post as written when you update it, and add the correction underneath.

I read this differently from hank_denver, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

Ask again with the specifics and you will get a better answer than this one.

Last edited: Dec 18, 2025 at 9:12 PM
3 3TirzTom, TrialTracker_MD, JennaRN
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Admin
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Dec 19, 2025 at 2:48 AM#20

Moderator note: the sourcing question belongs in the vendor section and has been split out.

Last edited: Dec 19, 2025 at 6:48 AM
31 6PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 28 others
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