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ForumsOral GLP-1 AgonistsHas anyone dealt with dropped my rybelsus in the toilet this morning - worst day? Page 2

Has anyone dealt with dropped my rybelsus in the toilet this morning - worst day?

MASHdoc_SA Tue, Jul 9, 2024 at 9:49 AM 41 replies 2,586 viewsPage 2 of 9
LabKate
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Jul 9, 2024 at 11:18 AM#6

Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

36 6JenMemphis, pat_auckland, Dr.GastroMayo and 33 others
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tyler_CSCS
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Jul 9, 2024 at 11:52 AM#7

A narrower follow-up, since the general answer is now clear:

Whether the fasting requirement is as strict in practice as the label implies, and what people actually see when they get it wrong?

35 5hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 32 others
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Dr.Martinez
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Jul 9, 2024 at 12:26 PM#8
LabKate said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Adding the part of the answer the thread has not reached. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

34 4rachel_ABQ, traveltech_sara, AttorneyGrant and 31 others
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MASHdoc_SA
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Jul 9, 2024 at 1:00 PM#9

OP back with an update, since a thread like this is useless without one.

Update — I went back to the injectable. Not because the tablet did not work, but because the fasting window and my mornings were never going to agree.

33 3LabKate, kate.chem, DataDave and 30 others
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carlos_SATX
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Jul 9, 2024 at 3:44 PM#10
Dr.Martinez said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

That is correct as far as it goes, and here is where it stops going. The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest. Where it bites is in the first fortnight, when people conclude the tablet does nothing.

Last edited: Jul 9, 2024 at 5:44 PM
43 18tommy_boulder, hyun_seoul, jim_asheville and 40 others
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