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ForumsPsychological & BehavioralGLP-1 and addiction pathways — anyone have experience? Page 2

GLP-1 and addiction pathways — anyone have experience?

sean_dublin Sun, Oct 12, 2025 at 7:36 PM 10 replies 1,203 viewsPage 2 of 2
DataDave
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Oct 14, 2025 at 1:01 AM#6
Dr.KarenChen said:
Before/after narrative for mental health — one year in: Before (260 lbs): Winded climbing stairs, chronic back pain, pre-diabetic, on 3 medications,…

This is where I part company with the consensus forming above. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.

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DanielChem_CHI
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Oct 14, 2025 at 12:45 PM#7
sean_dublin said:
The weight came off and the harder part started, which is not what any of the material I read had prepared me for.

Body image adjustment with mental health: I've lost 70 lbs but when I look in the mirror, I still see my old self sometimes. "Phantom fat" is a real phenomenon.

My therapist specializes in body image issues with weight loss patients. She says it can take 12-18 months for your brain's body map to update. In the meantime: take progress photos (your eyes lie but cameras don't), try on old clothes, and be patient with yourself.

Last edited: Oct 14, 2025 at 2:45 PM
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Dr.GutHealth
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Oct 15, 2025 at 12:28 AM#8
DataDave said:
I would be careful about how confidently the flatness reports get attributed.

When to call your doctor about mental health side effects — a reference I wish I'd had:

Call immediately:

  • Severe abdominal pain (could be pancreatitis)
  • Vision changes (thyroid concern)
  • Lump in neck (thyroid nodule)
  • Severe vomiting/can't keep fluids down for 24h+

Schedule an appointment:

  • Persistent nausea beyond 4 weeks
  • Significant hair loss
  • Mood changes or depression
  • Gallbladder symptoms (RUQ pain after eating)
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NurseAsh_DET
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Oct 15, 2025 at 12:11 PM#9

One thing that is still open after steve_okc’s answer:

Was that from a primary source or from a summary of one?

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sean_dublin
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Oct 17, 2025 at 8:25 PM#10

OP back with an update, since a thread like this is useless without one.

Follow-up — I put something in the gap where food used to be rather than waiting for the gap to close on its own. That was the part nobody told me.

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