Retatrutide anticipation thread — what are your questions for Phase 3?

rachel_ABQ said:

The useful move here is to separate what is established from what is widely repeated.

This matches mine closely enough to be worth saying so out loud. Posting only so the count is not one.

rachel_ABQ said:

The useful move here is to separate what is established from what is widely repeated.

Coming at rachel_ABQ’s question from a different direction. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

One thing that is still open after rachel_ABQ’s answer:

What would you measure differently if you were starting again?

OP back with an update, since a thread like this is useless without one.

Update — my curve sits below the published mean and the explanation is that the trial arm had support I do not have. That was reassuring rather than otherwise.