Amylin co-agonism: CagriSema REDEFINE results and implications

Dr.SportsMedIN said:

If two explanations both fit, the useful question is which one predicts something the other does not.

This matches mine closely enough to be worth saying so out loud. I had assumed I was the exception until I read this.

One thing that is still open after KevinCompounds’s answer:

Was that from a primary source or from a summary of one?

TrialTracker_MD said:

One habit that pays for itself: post the method alongside the number.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

Happy to go further on any of that.

TrialTracker_MD said:

One habit that pays for itself: post the method alongside the number.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

Moderator note: a couple of off-topic posts removed. No action needed from anybody.